INTRODUCING NO2… the first of an exciting new category of muscle-enhancers known as a hemodilators. NO2 has the unique ability to perpetually sustain the flow of muscle-building agents to skeletal muscle.

Now get faster, more dramatic increases in muscle size, strength and endurance plus full-body muscle recovery and the stunning new phenomenon known as the perpetual pump… all from the man who brought you creatine!

What is NO2 ?

NO2 has created a revolutionary new category of muscle-builders and muscle-enhancers known as “cell-signaling hemodilators”.

Through mediation of the “signaling-molecule” nitric oxide (NO), NO2 induces powerful hemodilation and creates dramatic increases in muscle size, strength, endurance, power output, and load capacity.

With its advanced sustained-release technology pHyser3, NO2 generates a virtual permanent muscle pump, now known as the “perpetual pump.”

NO2 was created by the same man who introduced Creatine to the market in 1993 – Ed Byrd, co-founder of EAS™ and now president of MRI™ (Medical Research Institute).

How NO2 works ?

NO2 creates – and sustains – levels of nitric oxide in the skeletal muscles.

Nitric oxide is the muscle’s “cell-signaling” molecule responsible for blood flow (hemodilation), oxygen delivery, glucose uptake, muscle velocity, power output, and muscle growth.

By creating and then sustaining levels of nitric oxide in the skeletal muscles NO2 delivers continuous muscle-enhancing benefits around the clock. Like amplifying muscle-growth signals for faster gains in lean mass, accelerating both fast and slow twitch muscle fiber for greater strength, providing complete “full-body muscle recovery”, and increasing endurance index (EI).

In addition, NO2′s sustained hemodilation (continuous and amplified blood-surge to the skeletal muscles) generates a “perpetual pump”.

Before the introduction of NO2, hemodilation occurred only during intense exercise, and lasted for a relatively brief time. Now, with NO2′s extended-release delivery system pHyser3, it is possible for hemodilation to last all day long! That means greater results and faster gains for you. And, of course, a “perpetual pump.”

The NO2 difference

The NO2 difference is this:

• No other supplement can sustain levels of nitric oxide AND generate a continual and amplified blood-surge (hemodilation) in skeletal muscles.

Until the creation of NO2′s extended-release delivery system (pHyser3), generating and maintaining nitric oxide levels was impossible. The human body’s pH factor literally dissolved any agent or substance that could help generate nitric oxide inside the body. Now, with NO2′s pH-corrected, body-compatible delivery system, pHyser3, the human body is
able to not only accept the nitric oxide delivery agent, but also sustain levels of nitric oxide in the muscles throughout
the entire day.

Now athletes and bodybuilders can finally get all the powerful benefits of hemodilation – all day long! Including faster gains in muscle mass, increased strength and endurance, and the creation of the “perpetual pump”.

Hemodilation

Hemodilation means a widening of the blood channels leading to skeletal muscles through the mechanism of amplified blood flow.

The word “Hemodilation” comes from combining ‘Hemo’ [from the Greek word 'haima' meaning blood] and ‘Dilator’ [from the Latin word 'dilatare' meaning to widen]. The measure of the widening of the blood canals is calculated by the “dilation differential™” – known as d-delta™.

Hemodilation is initiated by nitric oxide synthesis. Nitric oxide is the cell-signaling molecule responsible for blood flow, oxygen delivery, glucose uptake, muscle velocity, power output, and gene-expression, or muscle growth. By sustaining nitric oxide levels in the skeletal muscles, NO2 generates its sustained hemodilation. The channels that deliver muscle building agents to the muscle cells become forced open and remain that way throughout the day.
The results are faster gains in lean mass, greater strength, increased endurance, complete full-body muscle recovery, and a “perpetual pump.”

NOTE: Hemodilation is a new term that came into existence with the discovery of nitric oxide (NO). Under ordinary circumstances, hemodilation lasts only briefly. With the introduction of NO2, however, and the sustained NO levels it generates in the skeletal muscle, sustained hemodilation became a reality. The word hemodilation, as applied to NO2, means sustained hemodilation.

Hemodilation vs cell volumization

“What I started with Creatine, I perfected with NO2.” -Ed Byrd

How does NO2′s “hemodilation” compare to Creatine’s “cell-volumization”?

Because Ed Byrd introduced both Creatine and NO2, he says it best…

“As you probably know, Creatine causes ‘cell-volumizing’ by pulling water into the small space inside the muscle cell.
It does increase size, but you may look a little “puffy”. NO2′s hemodilation, on the other hand, creates genuine size by forcing blood into the vast and voluminous spaces between the muscle cells – not inside the cells.
This super-engorging creates massive pumps. What’s more, because the blood is between the cells not inside them, the pump is rock-hard – not at all puffy.

And with the extended-release delivery system pHyser3, the pump does not go away. You get what is known as a “perpetual pump”.

“Frankly, my recommendation to bodybuilders would be to take both Creatine and NO2. I look at it this way, what I started with Creatine, I perfected with NO2.”

What results should I see with NO2 ?

The first result most bodybuilders see (in 5-7 days) is the “perpetual pump.”

The perpetual pump is a massive rock-hard muscle pump that literally does not go away. Unlike the exercise-induced pump that quickly fades with time, the perpetual pump is virtually permanent.

Then, 2-3 days after the appearance of the perpetual pump, you’ll start noticing increases in strength and endurance.
At the same time, you’ll see increases in size in all your skeletal muscles.

Is NO2 right for me ?

Ask yourself these simple questions:

• Am I happy with my current muscle gains?
• Would I like to get the great-looking pump I get after an intense workout, and keep it all day long?
• Would I like to add more reps and more sets to every workout?

If you answered yes to any of these questions, NO2 is the perfect answer for you.

That’s because NO2 gives you:

• Continuous gains in lean mass by triggering forced-growth muscle-signaling action;
• A perpetual pump through its powerful hemodilating effects;
• Greater strength by accelerating your fast-twitch muscle strength; complete full-body muscle recovery; and
• Far better workouts by increasing your Endurance Index (EI).

Is NO2 safe ?

Yes. NO2 generates, and maintains, levels of nitric oxide – a substance that is totally natural to your body.

NOTE: There are now 3 categories of substances that help enhance performance: Drugs; Dietary Supplements; and now with the introduction of NO2 – Nutraceutical Expressors.

Drugs, like androgenic anabolic steroids, are foreign to your body. They work powerfully, but because they’re a foreign agent, they have many negative side effects. We do not recommend using drugs unless under a doctor’s supervision.

Dietary Supplements are naturally occurring substances in your body. They have a moderate range of effectiveness and usually have no side effects.

NO2 – the Nutraceutical Expressor™ – gives you the best of both worlds: powerful results and safety.

Nutraceutical Expressors work by amplifying both volume and action-time of muscle-building agents that are natural to your body. For example:

• Keeping nitric oxide in skeletal muscles for extended periods of time to effectively increase muscle-building protein synthesis
• Inducing sustained hemodilation; and
• Providing complete full-body muscle recovery

  are all examples of the benefits of Nutraceutical Expressors.

When should I take NO2 ?

For maximum results, refer to the chart below. You should start noticing results in about 5-7 days.

IMPORTANT: Remember to drink at least 64 ounces (that’s 8 glasses) of water daily while taking NO2.

Men

Women

Hemodilation

Hemodilation means a widening of the blood channels leading to skeletal muscles through the mechanism of amplified blood flow.

The word “Hemodilation” comes from combining ‘Hemo’ [from the Greek word 'haima' meaning blood] and ‘Dilator’ [from the Latin word 'dilatare' meaning to widen]. The measure of the widening of the blood canals is calculated by the “dilation differential™” – known as d-delta™.

Hemodilation is initiated by nitric oxide synthesis. Nitric oxide is the “cell-signaling” molecule responsible for blood flow, oxygen delivery, glucose uptake, muscle velocity, power output, and gene-expression, or muscle growth. By sustaining nitric oxide levels in the skeletal muscles, NO2 generates its sustained hemodilation. The channels that deliver muscle building agents to the muscle cells become “forced open” and remain that way throughout the day. The results are faster gains in lean mass, greater strength, increased endurance, complete full-body muscle recovery, and a “perpetual pump.”

NOTE: Hemodilation is a new term that came into existence with the discovery of nitric oxide (NO). Under ordinary circumstances, hemodilation lasts only briefly. With the introduction of NO2, however, and the sustained NO levels it generates in the skeletal muscle, sustained hemodilation became a reality. The word hemodilation, as applied to NO2, means sustained hemodilation.

Perpetual pump

A “perpetual pump” is a muscle pump that remains in its post-exercise, blood-engorged, rock-hard condition virtually all the time! The increased muscle size and muscle density achieved through exercise do not fade with time.

The “perpetual pump” is a brand new phenomenon. It’s one of the stunning effects of the sustained hemodilation you get from NO2.

Increased blood flow is responsible for your pump. Your body responds to exercise by releasing nitric oxide, the muscle’s “signaling molecule” responsible for increased blood flow.

When you exercise hard, Nitric oxide opens the blood floodgates, allowing blood to surge in. That’s hemodilation, and that’s how you get a “pump”. But the exercise-induced pump is only temporary. It disappears soon after the body realizes exercise has ended.

Now, with NO2, pumps do not go away. Even massive, vein-popping pumps show no sign of diminishing.
That’s because NO2 generates a continuous surge of blood that courses through the skeletal muscle throughout the day. So muscles remain engorged and steel-like all day long. The secret of the continuous surge of blood lies in NO2′s exclusive nitric oxide extended-release delivery system pHyser3.

Muscle Fiber Twitch Accelerators

These accelerators are any agent or substance capable of increasing the contractile velocity of both fast and slow twitch muscle fibers.

By increasing nitric oxide production, NO2 increases your maximum contractile velocity – in all muscle types.
Fast-twitch fibers get faster. Slow-twitch fibers start acting more like fast-twitch.

The results are immediate and consequential, and include increasing your load capacity, boosting your power output, and quickening your muscle contraction.

Endurance index (EI)

The Endurance Index (EI) is the new measure of the rate of increased endurance during work output.

Current research indicates that the keto-acids, like the ones you find in NO2, can help significantly delay fatigue and dramatically improve your Endurance Index (EI).

In fact, many athletes are now reporting that taking NO2 gives them the kind of endurance they get when they train at high altitude and then race at sea level.

Providing Full-Body Muscle Recovery

Muscle recovery refers to the difference in blood channel diameter between normal conditions and hemodilated conditions. The greater the dilation (d), the greater the blood-surge to the skeletal muscle. The difference between any two sizes of dilation is called the differential (dD).

NO2′s increase in the dilation differential is what generates the new condition known as the “perpetual pump.”

The new full-body muscle recovery is one that provides all skeletal muscles with a complete recovery.
That includes both the smaller and larger muscle groups.

Full-body muscle recovery allows all the muscles on your body grow in the correct proportion to each other – providing a better and more proportional physique.

NOTE: The continual surge of blood that NO2 supplies muscles gives them the time they need to recover completely. Compare that to the normal recovery time of about 30-45 minutes. NO2′s “amplified” surge of blood and the greater dilation it creates (known as “dD” – dilation differential), “forces” blood to all the muscles not just the larger ones.
That gives all skeletal muscles a complete recovery.

Dilation Differential (dD)

Dilation Differential is the difference in blood channel diameter between normal conditions and hemodilated conditions. The greater the dilation (d), the greater the blood-surge to the skeletal muscle.
The difference between any two sizes of dilation is called the differential (dD).

NO2′s increase in the dilation differential is what generates the new condition known as the “perpetual pump.”

Nutraceutical Expressors

Nutraceutical Expressors dramatically amplify both the volume and action-time of natural muscle-building agents.
For example, NO2 helps keep nitric oxide in skeletal muscle for extended periods of time to effectively increase time of muscle-building protein synthesis, induce sustained hemodilation, provide full-body muscle recovery, accelerate muscle fiber twitch, and increase endurance index.

NOTE: There are now 3 categories of substances that help enhance performance: Drugs; Dietary Supplements; and now with the introduction of NO2 – Nutraceutical Expressors.

Drugs, like androgenic anabolic steroids, are foreign to your body. They work powerfully, but because they’re a foreign agent, they have many negative side effects. We do not recommend using drugs unless under a doctor’s supervision.

Dietary Supplements are naturally occurring substances in your body. They have a moderate range of effectiveness and usually have no side effects.

NO2 – the Nutraceutical Expressor™ – gives you the best of both worlds: powerful results and safety.

Dillation Differential

Dilation Differential is the difference in blood channel diameter between normal conditions and hemodilated conditions. The greater the dilation (d), the greater the blood-surge to the skeletal muscle. The difference between any two sizes of dilation is called the differential (dD).

NO2′s increase in the dilation differential is what generates the new condition known as the “perpetual pump.”

Gene Expression (re-defined)

“Gene expression” is not a new term. But it now has new meaning thanks to NO2.

In fact, it is the standard term used to describe the activation of any gene responsible for a specific function – like constructing new muscle.

Gene expression, when used in the context of NO2, however, takes on a new meaning. It refers to sustained gene expression, and therefore, the sustained muscle growth it provides.

pHyser³™ (delivering the undeliverable)

pHyser³ represents a major breakthrough in the effective delivery muscle-building agents. pHyser³ allows the delivery of agents previously thought to be undeliverable.

MRI’s new pHyser³ is a pH-corrected, body-compatible delivery system that allows the human body to fully accept the nitric oxide delivery agent, unlocking the full potential of nitric oxide’s powerful effect on skeletal muscle.

In addition, its extended-release delivery mechanism ensures that nitric oxide levels are maintained and sustained for the entire day. That’s how NO2 creates a steady and continuous blood-surge to the skeletal muscles. Creating greater size, strength, endurance, and the “perpetual pump.”

pHyser³ was created by the Medical Research Institute (MRI) in Northern California. MRI’s president and CEO is Ed Byrd, co-founder of EAS™ and the man whose company introduced the last significant breakthrough in sports supplements in 1993 – creatine monohydrate.

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